James Heald

I am a Research Fellow in Theoretical Neuroscience working with Maneesh Sahani at the Gatsby Computational Neuroscience Unit, UCL. Previously, I worked as a postdoctoral researcher at the Zuckerman Mind Brain Behavior Institute, Columbia University with Daniel Wolpert.

I received a PhD in Engineering from the University of Cambridge, where I trained in the Computational and Biological Learning Lab under the supervision of Daniel Wolpert (primary supervisor) and Máté Lengyel (secondary advisor). Prior to my PhD, I worked as a medical doctor in the NHS, and before that, I received an MSc in Cognitive and Computational Neuroscience from The University of Sheffield and an MBChB in Medicine from The University of Manchester.

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Research

I study motor control in brains and machines by applying ideas from reinforcement learning and probabilistic machine learning. My research interests lie at the intersection of biological and machine learning.

Competitions

MyoChallenge 24: Physiological Dexterity and Agility in Bionic Humans
Team Muscle Heads: James Heald, Kai Biegun, Samo Hromadka, Maneesh Sahani
NeurIPS 2024 Competition Track Program

Our team came first place in the NeurIPS 2024 MyoChallenge Manipulation Track. The challenge involved coordinating a biologically-realistic arm with 63 muscles and a robotic prosthetic arm with 17 DoFs to transfer an object between two pillars. The object properties and pillar locations were randomized on each episode. To control the musculoskeletal arm, we trained a policy that recruited muscles in a coordinated manner using learned muscle synergies. This allowed us to efficiently acquire dexterous reaching and grasping skills. To control the robotic prosthetic arm, we combined a learned policy with inverse kinematic control, enabling smooth hand-offs and object relocation. Curriculum learning and reward shaping were used to solve the task in stages (reach, grasp, handover, move object to goal) .

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Our winning solution, showcasing robustness to random pillar locations and object properties (weight, size and friction).

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Our solution ranked first on all metrics: score, time, effort and peak contact force.

Select publications

Representative papers are highlighted.

arn image The computational and neural bases of context-dependent learning
James Heald, Daniel Wolpert*, Máté Lengyel*
Annual Review of Neuroscience, 2023

We review a theoretical approach to formalizing context-dependent learning in the face of contextual uncertainty and the core computations it requires. We show how this approach organizes a large body of disparate experimental observations, from multiple levels of brain organization (including cells, circuits, systems and behavior) and multiple brain regions (most prominently the prefrontal cortex, the hippocampus and motor cortices), into a coherent framework. We argue that contextual inference may also be key to understanding continual learning in the brain.

tics image Contextual inference in learning and memory
James Heald, Máté Lengyel*, Daniel Wolpert*
Trends in Cognitive Sciences, 2023   (Feature Review and Issue Cover)
PDF / Issue Cover

In this issue of Trends in Cognitive Sciences, we review a computational framework of repertoire learning that provides a unifying account of phenomena across numerous domains, including conditioning, episodic memory, economic decision making and motor learning.

coin image Contextual inference underlies the learning of sensorimotor repertoires
James Heald, Máté Lengyel*, Daniel Wolpert*
Nature, 2021   (accompanied by News and Views)
PDF / Code / Data / New and Views

We develop a theory of motor learning based on the principle of contextual inference. Our theory reveals that adaptation can arise by both creating and updating memories and changing how existing memories are differentially expressed.

control points image Multiple motor memories are learned to control different points on a tool
James Heald, James Ingram, J. Randall Flanagan, Daniel Wolpert
Nature Human Behaviour, 2018
PDF / Code

Different parts of tools are often handled in different ways. This study presents a computational model explaining how humans build separate motor memories for different parts of the same object.


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